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April 19, 2022Innate Immunity May Also Have Immune Memory
In the past, only the adaptive immune system was considered to create new immune memory (via antigen-antibody interactions) and update its function after novel experiences. Recent studies, however, suggest that innate immunity can also be ‘trained’ by immune events and exposures.
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March 24, 2022Webinar Replay: Clinical Management of the Sleep-Immune Connection
Missed the live event? Want a refresher? Come listen to Dr. Jeffrey Bland talk about the ways our immunity and sleep connect…
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February 18, 2022Polyphenols Help Maintain Immune Equilibrium
Regulation of the immune response occurs through the collective actions of signaling pathways that direct innate and adaptive immune function. This review examines how dietary polyphenolic substances (quercetin, resveratrol, and others) affect immune signaling networks implicated in the development of autoimmune dysfunction.
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February 8, 2022Webinar Replay: Himalayan Tartary Buckwheat and Omega-3 Rejuvenate for Healthy Weight Control
Missed the live event? Want a refresher? Come listen to Dr. Jeffrey Bland talk about the ways our immune system can contribute to a healthy weight …
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January 17, 2022Webinar Replay: Dr. Jeff Bland and Dr. Robert Silverman on Omega 3s — What You Need to Know
Missed the live event? Want a refresher? Come listen to Dr. Jeffrey Bland and Dr. Robert Silverman talk about the ways our immune systems are affected by food, and how all omega-3 fish oils are not created equal …
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January 6, 2022Dr. Mark Hyman: The Difference Between Rejuvenating and Boosting Your Immune System
How rejuvenation happens inside your body, and how to switch it on …
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December 21, 2021EPA and DHA Attenuate Stress-Induced Vascular Senescence
This 12-week clinical trial of time-restricted but not energy-restricted eating in overweight and obese adults demonstrates that even a limited period of time-restricted eating (TRE) can improve weight and body composition in these individuals. It further establishes that TRE is a feasible approach to managing behaviors that impact glucose metabolism and risk for inflammatory and cardiometabolic disorders.
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December 15, 2021EPA and DHA Affect Skin Immune Response Differently
This 12-week clinical trial of time-restricted but not energy-restricted eating in overweight and obese adults demonstrates that even a limited period of time-restricted eating (TRE) can improve weight and body composition in these individuals. It further establishes that TRE is a feasible approach to managing behaviors that impact glucose metabolism and risk for inflammatory and cardiometabolic disorders.
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December 6, 2021TRE May Help Remodel Eating Behaviors
This 12-week clinical trial of time-restricted but not energy-restricted eating in overweight and obese adults demonstrates that even a limited period of time-restricted eating (TRE) can improve weight and body composition in these individuals. It further establishes that TRE is a feasible approach to managing behaviors that impact glucose metabolism and risk for inflammatory and cardiometabolic disorders.
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December 6, 2021Dietary Polyphenols Affect Both Commensals and Pathogens in the Gut
This meta-analysis identifies dietary polyphenols that exert significant influence on the intestinal abundance of probiotic Lactobacillus and Bifidobacterium species as well as various pathogenic and beneficial Clostridium species. From data derived by the analysis, the authors estimate daily polyphenol intakes most closely associated with specific improvements in gut microbiota composition.
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November 29, 2021EPA’s Impact on Mood
This meta-analysis of 26 randomized, double-blind, placebo-controlled trials concluded that a daily dosage of ≤1 gram of eicosapentaenoic acid (EPA) provided in omega-3 formulations consisting of at least 60% EPA showed significant benefit in 2160 with depression or depressive symptoms, compared to placebo. The authors discussed several mechanisms for the efficacy of EPA in addressing mood.
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November 15, 2021Higher Flavonoid Intake Linked to Better Cognitive Function
Greater consumption of flavonoid-rich foods has been linked to cognitive health, and this study highlights the special contributions of quercetin, anthocyanins, catechins, flavonols, and flavanones to these findings. These flavonoids are found in berries, green and black tea, citrus fruits, buckwheat, cruciferous vegetables, and other deeply-colored fruits and vegetables.
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October 26, 2021Webinar Replay: Twincretins and Nutritional Therapy
Missed the live event? Want a refresher? Come listen to Dr. Jeffrey Bland talk about twincretins — what they are, and how to use them in nutritional therapies. If you’re hearing more and more about glucagon-like peptide 1 (GLP1) and insulin sensitivity, then twincretins will matter to you and your patients …
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October 25, 2021Omega-3s as Potential Prebiotics
This clinical trial is among the first to demonstrate that supplementation with omega-3 fatty acids, even at a moderate daily dosage of 500 milligrams, alters the gut microbiome and intestinal fermentation processes in ways that may partly account for the well-known cardiovascular benefits of omega-3s.
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October 25, 2021How Plant Polyphenols Benefit Plants—and Their Consumers
This review examines the dual nature of polyphenolic substances created by food plants: protecting growing plants to ensure their survival and enhancing these foods’ nutritional and health advantages for consumers.
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October 19, 2021Omega-3s Coordinate Innate and Adaptive Immune Teamwork
Omega-3 fatty acids are known to be incorporated into the cell membranes of every type of immune cell tested. Many immune cells possess enzymes needed to produce omega-3 metabolites called specialized pro-resolving mediators (SPMs/PRMs), which in turn regulate their function. This review details how omega-3s (mainly eicosapentaenoic and docosahexaenoic acids, EPA and DHA) influence the activity and genetic expression of immune cells from both innate and adaptive compartments of the immune system.
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October 11, 2021Exposure to Forest Biodiversity Encourages Immune Regulation
Time spent in natural outdoors settings is a crucial immune-regulating experience for urban dwellers, and especially for children. Direct exposure to forest biomes—or even just forest floor vegetation and dirt—is an effective means of altering balance among circulating immune factors (interleukins, regulatory T cells, etc.) that are key to developing immune tolerance. Biodiversity intervention is of growing importance for the management of dysbiosis and immune imbalance.
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October 11, 2021Omega-3 Supplementation Reprograms the Immune Response
Omega-3 fatty acids like EPA, DHA, and DPA have demonstrated many direct benefits to immune, cardiovascular, and neurocognitive health. Their nutritional influence extends further, however, through the actions of their specialized pro-resolving mediator (SPM/PRM) metabolites.
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September 29, 2021Brain Health across the Lifespan: A Systematic Review on the Role of Omega-3 Fatty Acid Supplements
“Bearing in mind the scale of ageing populations and rising healthcare costs linked to poor brain health, omega supplementation could be a useful strategy for helping to augment dietary intakes and support brain health across the lifespan. Ongoing research is now needed using harmonious methodologies, supplement dosages, ratios and intervention periods to help formulate congruent conclusions.”
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September 27, 2021Healthy Effects of Plant Polyphenols: Molecular Mechanisms
“The findings reported in the last decade are starting to help to decipher the complex relations between plant polyphenols and cell homeostatic systems including metabolic and redox equilibrium, proteostasis, and the inflammatory response, establishing an increasingly solid molecular basis for the healthy effects of these molecules. Taken together, the data currently available, though still incomplete, are providing a rationale for the possible use of natural polyphenols, or their molecular scaffolds, as nutraceuticals to contrast aging and to combat many associated pathologies.”
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