Publications
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Brain Health across the Lifespan: A Systematic Review on the Role of Omega-3 Fatty Acid Supplements
“Bearing in mind the scale of ageing populations and rising healthcare costs linked to poor brain health, omega supplementation could be a useful strategy for helping to augment dietary intakes and support brain health across the lifespan. Ongoing research is now needed using harmonious methodologies, supplement dosages, ratios and intervention periods to help formulate congruent conclusions.”
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Healthy Effects of Plant Polyphenols: Molecular Mechanisms
“The findings reported in the last decade are starting to help to decipher the complex relations between plant polyphenols and cell homeostatic systems including metabolic and redox equilibrium, proteostasis, and the inflammatory response, establishing an increasingly solid molecular basis for the healthy effects of these molecules. Taken together, the data currently available, though still incomplete, are providing a rationale for the possible use of natural polyphenols, or their molecular scaffolds, as nutraceuticals to contrast aging and to combat many associated pathologies.”
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Associations of Omega-3 fatty acids with brain morphology and volume in cognitively healthy older adults: A narrative review
“Substantial research has aimed to discover the reasons why some people experience greater morphologic changes that produce undesirable consequences with aging and how it may be prevented. One possible explanation is diet, particularly fish consumption and the intake of omega-3 polyunsaturated fatty acids (omega 3) concentrated in fish oil.”
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Beneficial Outcomes of Omega-6 and Omega-3 Polyunsaturated Fatty Acids on Human Health: An Update for 2021
“PUFAs display a plethora of biological activities at the molecular and cellular levels that result in effects on cell and tissue function linked to health outcomes and disease risk. Antioxidant and anti-inflammatory properties of omega-3 PUFAs are important and are recognized as contributing to reduced disease risk and severity (i.e., better health).”
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The prebiotic effects of omega-3 fatty acid supplementation: A six-week randomised intervention trial
“Dietary omega-3 alters gut microbiome composition and some of its cardiovascular effects appear to be potentially mediated by its effect on gut microbial fermentation products indicating that it may be a prebiotic nutrient.”
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Polyphenols and Human Beings: From Epidemiology to Molecular Targets
“Dietary polyphenols have been associated with health benefits in the prevention of a range of degenerative and age-related diseases that constitute the major causes of death and incapacitation in developed countries.”
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Using an erythrocyte fatty acid fingerprint to predict risk of all-cause mortality: the Framingham Offspring Cohort
“The objective of this study was to compare a combination of RBC FA levels with standard risk factors for cardiovascular disease (CVD) in predicting risk of all-cause mortality.”
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Extraoral bitter taste receptors in health and disease
“Good medicine always tastes bitter.” This ancient Oriental wisdom may soon be verified with modern biology. Traditionally, bitter taste, one of five basic taste qualities, is thought to guide organisms to avoid harmful toxins and noxious substances and thus is critical to animal and human survival.”
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An aged immune system drives senescence and ageing of solid organs
“These data demonstrate that an aged, senescent immune system has a causal role in driving systemic ageing and therefore represents a key therapeutic target to extend healthy ageing.”
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Immunoresolvents signaling molecules at intersection between the brain and immune system
“The present brief review discusses evidence for the crosstalk between the nervous system and leukocytes in regulating SPM production.”
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Protectin D1n-3 DPA and resolvin D5n-3 DPA are effectors of intestinal protection
“We provide evidence for a functional role of bioactive lipid mediators of the docosapentaenoic acid (DPA) metabolome in intestinal inflammation.”
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Effectiveness of rutin-rich Tartary buckwheat (Fagopyrum tataricum Gaertn.) ‘Manten-Kirari’ in body weight reduction related to its antioxidant properties: A randomised, double-blind, placebo-controlled study
“Rutin, a phenolic compound, has antioxidant, anti-dyslipidaemic, and body weight-reducing effects. We evaluated the anti-arteriosclerotic, antioxidant, and body weight-reducing effects of rutin-rich Tartary buckwheat.”
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Effects of common and Tartary buckwheat consumption on mucosal symptoms, headache and tiredness: A double-blind crossover intervention study
“Buckwheat is rich in the flavonoid rutin and other compounds beneficial to human health. Buckwheat is used traditionally as a health food in the treatment of different diseases, but there have been few studies of its effects on symptoms and well-being. “
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Nutrient components and bioactive compounds in tartary buckwheat bran and flour as affected by thermal processing
“In the present study, the contents of amino acids, fatty acids, polysaccharides, polyphenols, and flavonoids were compared in tartary buckwheat bran and flour before and after baking.”
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Comparison of Plant Morphology, Yield and Nutritional Quality of Fagopyrum esculentum and Fagopyrum tataricum Grown under Field Conditions in Belgium
“Buckwheat is a pseudocereal with high nutritional and nutraceutical properties. Althoughcommon buckwheat (Fagopyrum esculentum) is the main cultivated species, Tartary buckwheat(Fagopyrum tataricum) is gaining interest”
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