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Big Bold Health Professional

Microbiome Rejuvenate™

Microbiome Rejuvenate™

Microbiome Rejuvenate is an exclusive formula designed around unique prebiotic nutrients found in the bran of Himalayan Tartary Buckwheat. It also contains BetaVia™ Complete, a clinically studied microalgae prebiotic, as well as the probiotic Lactobacillus rhamnosus to nourish the gut microbiome. With the addition of two key polyphenols (quercetin and luteolin), Microbiome Rejuvenate is your one-stop shop for gut-immune support.*

  • An exclusive formula powered by unique prebiotic nutrients found in organic Himalayan Tartary Buckwheat Bran
  • Includes 5 billion CFU of Lactobacillus Rhamnosus (CRL 1505) per serving, a probiotic clinically linked to improved immune balance
  • Contains BetaVia™ Complete (Beta Glucans), a clinically studied prebiotic linked to improved immune resilience
  • Includes the potent polyphenols Quercetin and Luteolin for extra phytonutrient and microbiome support
Nutritional uses of 2-HOBA are licensed to Big Bold Health® under U.S. Patent Nos. 7,705,054 and 8,822,542
Nutritional uses of HMB and Vitamin D are licensed to Big Bold Health® under U.S. Patent # 8,815,280, # 9,259,430, #9,539,224, #9,707,241, #9,770,424 and #10,201,551
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What is it?


A custom blend of the phytonutrients and prebiotics found in Himalayan Tartary Buckwheat bran with additional pre- and probiotics.

Contains 5 billion CFU per serving of Lactobacillus rhamnosus CRL 1505, a clinically proven probiotic.

Contains BetaVia™ Complete, a clinically proven prebiotic with beta glucans from microalgae.

Contains quercetin and luteolin as additional polyphenols.

Third-party tested for purity and potency.

Non-GMO, vegetarian, dairy-free, and gluten-free.

Cost per day is just $1.35 with subscription.

How do I use it?


Take 2 capsules every day, with or without food.

One bottle contains 120 capsules for 60 servings or a 2 month supply.

We recommend daily usage on an ongoing basis to support immune function and promote rejuvenation of your immune response.*

What are the health benefits?


Stronger immune performance*

Better immune balance*

Support for gut immunity*

Support for gut & microbiome health*

Show me the science.


Here's a sample of the scientific literature that supports this product.

- Flavonoids in common and tartary buckwheat hull extracts and antioxidant activity of the extracts against lipids. J Food Sci Tech 2019. Park BI et al. Click to read the study.

- Polyphenols-gut microbiota interrelationship: A transition to a new generation of prebiotics. Nutrients 2021. Plamada D et al. Click to read the study.

- Dietary polyphenol, gut microbiota, and health benefits. Antioxidants 2022. Wang X et al. Click to read the study.

- Probiotics for everyone: The novel immunobiotic Lactobacillus rhamnosus CRL1505 and the beginning of social probiotic programs in Argentina. Intl J Biot Well 2012. Villena JC et al. Click to read the study.

- Effect of a Euglena gracilis fermentate on immune function in healthy, active adults: A randomized, double-blind, placebo-controlled trial. Nutr 2019. Evans M et al. Click to read the study.

- Effect of food containing paramylon derived from Euglena gracilis EOD-1 on fatigue in healthy adults: A randomized, double-blind, placebo-controlled, parallel-group trial. Nutr 2020. Kawano T et al. Click to read the study.

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