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Big Bold Health Professional

HTB Rejuvenate™

HTB Rejuvenate™

Himalayan Tartary Buckwheat is a food crop that has been grown for centuries in some of the most challenging climates in the world. Twenty-first century technology is revealing the unique nutrient characteristics of this plant, including an array of phytonutrients that have been shown to have health-promoting effects on immunity, metabolism, and cellular rejuvenation. *

HTB Rejuvenate™ is a proprietary blend of phytonutrients and bioactive molecules that naturally occur in Himalayan Tartary Buckwheat, including an exclusive ingredient called 2-hydroxybenzylamine (2-HOBA). 2-HOBA has a special relationship with the immune system, supporting brain cells, DNA, muscles, enzymes, nerves, and chemical messengers. This product also features calcium salt of β-Hydroxy β-methylbutyric acid (HMB) for muscle support. *

  • Unique Phytonutrient Blend
  • Gluten-Free
  • Non-GMO
  • Vegetarian
Nutritional uses of 2-HOBA are licensed to Big Bold Health® under U.S. Patent Nos. 7,705,054 and 8,822,542
Nutritional uses of HMB and Vitamin D are licensed to Big Bold Health® under U.S. Patent # 8,815,280, # 9,259,430, #9,539,224, #9,707,241, #9,770,424 and #10,201,551
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What is it?


A custom blend of phytonutrients that naturally occur in Himalayan Tartary Buckwheat, an ancient food crop used as medicine in traditional cultures.

Contains nearly 600 mg per serving of immune-active plant polyphenols like quercetin, rutin, luteolin, and hesperidin.

Contains hobamine® (2-hydroxybenzylamine), a molecule involved with cell health.

Contains D-chiro-inositol, a molecule involved with blood sugar regulation.

Third-party tested for purity and potency.

Non-GMO, vegetarian, dairy-free, and gluten-free.

Cost per day is just $1.16 with subscription.

How do I use it?


Take 2 capsules every day, with or without food.

One bottle contains 120 capsules for 60 servings or a 2 month supply.

We recommend daily usage on an ongoing basis to support immune function and promote rejuvenation of your immune response.*

What are the health benefits?


Stronger immune performance*

Better immune balance*

Helps combat oxidative stress*

Maintains healthy blood sugar levels*

Support for gut & microbiome health*

Show me the science.


Here's a sample of the scientific literature that supports this product.

- Buckwheat bioactive compounds, their derived phenolic metabolites and their health benefits. Mol Nutr Food Res 2017. Giménez-Bastida JA et al. Click to read the study.

- Shaping a sustainable food future by rediscovering long-forgotten ancient grains. Plant Sci 2018. Cheng A. Click to read the study.

- Treasure from garden: Bioactive compounds of buckwheat. Food Chem 2021. Huda MN et al. Click to read the study.

- Rewiring of the seed metabolome during Tartary buckwheat domestication. Plant Biotechnol J 2022. Zhao H et al. Click to read the study.

- Chemical composition and health effects of Tartary buckwheat. Food Chem 2016. Zhu F. Click to read the study.

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